Toxina Botulínica Tipo A NB 100U - Nabota

<p><span style="color: rgb(0, 0, 0); font-family: arial, helvetica, sans-serif; font-size: 14px; orphans: 2; widows: 2;">A toxina botul&iacute;nica &eacute; indicada para amenizar linhas de express&atilde;o e rugas profundas. al&eacute;m, de ser muito usada para Hiperidrose.</span></p><div class="product-not-sale" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><div data-url-pricebox="/mvc/store/product/variant_price/?loja=1015578" id="product-priceBox" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><div class="produto-preco bg-tone-5 border-tone-5" data-app="product.price-box" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><div align="left" id="preco" style="margin: 30px 0px 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><div id="produto_preco" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box; color: #393939; font-family: Inter, sans-serif; font-size: 16px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: -webkit-left; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: #ffffff; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;"><h5 class="produto-economize" id="economize" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Com in&iacute;cio de suas vendas no Brasil em outubro de 2020, a Nabota&reg; &eacute; a nova gera&ccedil;&atilde;o de toxina desenvolvida pela pela Daewong Pharmaceutics, uma das maiores empresas de medicamentos do mundo.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Possui garantia de efic&aacute;cia e seguran&ccedil;a, com aprova&ccedil;&atilde;o pelos dois maiores criteriosos &oacute;rg&atilde;os de regulamenta&ccedil;&atilde;o do mundo, o FDA e CE. Foram realizados estudos cl&iacute;nicos na Europa, Canad&aacute; e EUA, com mais de 2 mil pacientes em 68 multicentros.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Nabota&reg; tamb&eacute;m apresenta grande diferencial, com taxa de efic&aacute;cia de 93,8% e no grupo de pacientes a partir de 65 anos demonstrou uma excelente taxa de melhora de 81,3%.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Outro diferencial &eacute; o r&aacute;pido in&iacute;cio da a&ccedil;&atilde;o. A partir do 2 dia ap&oacute;s aplica&ccedil;&atilde;o, Nabota&reg; apresenta uma taxa de melhora de 85,3% enquanto alguns de seus concorrentes apresentam taxa de melhora a partir do 5 dia ap&oacute;s aplica&ccedil;&atilde;o.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* A sua inova&ccedil;&atilde;o tamb&eacute;m est&aacute; presente no sistema ABRE F&Aacute;CIL com possibilita 100% do aproveitamento do produto.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* A Nabota&reg; tem a vantagem de ser uma toxina precisa e previs&iacute;vel, com menor halo de a&ccedil;&atilde;o quando comparado aos seus principais concorrentes. Com isso, apresenta menor probabilidade de eventos adversos.</span><br />&nbsp;</h5><h5 class="produto-economize" style="margin: 0px; padding: 0px; outline: 0px; box-sizing: border-box;"><br /><strong font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">Composi&ccedil;&atilde;o:</strong><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Toxina botul&iacute;nica A 100 unidades, excipientes q.s.p. 1 frasco-ampola (albumina humana e cloreto de s&oacute;dio).</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Conservar entre 2 e 8&deg;C, em seu frasco original n&atilde;o aberto.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Ap&oacute;s preparo, manter refrigerado entre 2 e 8&deg;C por at&eacute; 24 horas.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Reconstitui&ccedil;&atilde;o - T&eacute;cnica de Dilui&ccedil;&atilde;o.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* T&eacute;cnica de Dilui&ccedil;&atilde;o Nabota&reg; deve ser reconstitu&iacute;do com a solu&ccedil;&atilde;o salina &ndash; soro fisiol&oacute;gico 0,9%, est&eacute;ril de acordo com a tabela de dilui&ccedil;&atilde;o e com a t&eacute;cnica profissional.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Garante extra&ccedil;&atilde;o total com 100% de aproveitamento do produto:</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Abrir o Lacre.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Utilizar o pr&oacute;prio dispositivo para retirar a tampa.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Retirar completamente o lacre.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Retirar a tampa de borracha.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Advert&ecirc;ncia: N&atilde;o abrir o lacre antes de ser reconstitu&iacute;do. Armazenamento e Manuseio:</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Conservar entre 2 e 8&deg;C, em seu frasco original n&atilde;o aberto.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Ap&oacute;s preparo, manter refrigerado entre 2 e 8&deg;C por at&eacute; 24 horas.</span><br />&nbsp;</h5><p><strong font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">Especifica&ccedil;&otilde;es T&eacute;cnicas:</strong><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* 100U.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Ingrediente Ativo: Toxina Clostridium.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Tamanho Complexo: 900kDa.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Apar&ecirc;ncia: P&oacute; branco liofilizado.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Pot&ecirc;ncia: 1 U = LD50.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Armazenamento: 2-8&ordm;C.</span><br font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="" /><span font-size:="" font-variant-ligatures:="" helvetica="" letter-spacing:="" orphans:="" sans="" source="" style="color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:="">* Validade: 3 anos ap&oacute;s a data de fabrica&ccedil;&atilde;o.</span></p><p>&nbsp;</p><div aria-expanded="true" aria-selected="true" class="accordion-title allow active" data-collapsible="true" data-role="collapsible" font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" role="tab" sans="" source="" style="letter-spacing: 0.28px; padding: 10px 16px; cursor: pointer; position: relative; border-bottom-width: 2px; border-bottom-style: solid; border-bottom-color: rgb(237, 238, 240); color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:=""><div data-role="trigger" id="tab-label-product.info.aplicacao-title" style="letter-spacing: 0.02em; margin: 0px; font-size: 1.4rem; font-weight: 600;" tabindex="0"><div style="letter-spacing: 0.02em; margin: 0px; font-size: 1.4rem;">Aplica&ccedil;&atilde;o</div></div></div><div aria-hidden="false" aria-labelledby="tab-label-product.info.aplicacao-title" class="accordion-content" data-role="content" font-size:="" font-variant-ligatures:="" helvetica="" orphans:="" role="tabpanel" sans="" source="" style="letter-spacing: 0.28px; color: rgb(51, 68, 87); font-family: " text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" widows:=""><div class="accordion-content-inner" style="letter-spacing: 0.02em; padding: 16px;"><div class="product attribute aplicacao" style="letter-spacing: 0.02em;"><div class="value" style="letter-spacing: 0.02em;"><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">A&nbsp;<strong style="letter-spacing: 0.02em;">Nabota</strong>&reg; &eacute; um complexo de&nbsp;<strong style="letter-spacing: 0.02em;">Toxina Butol&iacute;nica A 100U&nbsp;</strong>da&nbsp;<strong style="letter-spacing: 0.02em;">Rennova</strong>, ultra purificada a partir da cepa Hall de clostridium botulinum tipo A. Foi desenvolvida para auxiliar na melhora tempor&aacute;ria na apar&ecirc;ncia de rugas glabelares moderadas e severas, associadas a atividade dos m&uacute;sculos corrugador e pr&oacute;cero em adultos e no tratamento da espasticidade focal dos nervos superiores associada a acidente vascular cerebral em adultos.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">&nbsp;</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;"><strong style="letter-spacing: 0.02em;">Contraindica&ccedil;&otilde;es:</strong></p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">NABOTA&reg; n&atilde;o deve ser utilizado:<br style="letter-spacing: 0.02em;" />Por pacientes com hipersensibilidade a qualquer componente deste produto.<br style="letter-spacing: 0.02em;" />Por pacientes com disfun&ccedil;&otilde;es na jun&ccedil;&atilde;o neuromuscular (ex. miastenia grave, s&iacute;ndrome de LambertEaton ou esclerose lateral amiotr&oacute;fica).<br style="letter-spacing: 0.02em;" />Em mulheres gr&aacute;vidas, lactantes ou com planos de engravidar.<br style="letter-spacing: 0.02em;" />Em pacientes com hiperatividade neurog&ecirc;nica do m&uacute;sculo detrusor que tamb&eacute;m apresentam infec&ccedil;&atilde;o aguda do trato urin&aacute;rio.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">&nbsp;</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;"><strong style="letter-spacing: 0.02em;">Rea&ccedil;&otilde;es Adversas:</strong></p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">Podem ocorrer rea&ccedil;&otilde;es de hipersensibilidade, como anafilaxia, urtic&aacute;ria, edema de tecidos moles e dispneia, al&eacute;m de outros tipos de rea&ccedil;&otilde;es adversas.<br style="letter-spacing: 0.02em;" />Para mais informa&ccedil;&otilde;es, vide a Bula.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">&nbsp;</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;"><strong style="letter-spacing: 0.02em;">Intera&ccedil;&otilde;es:</strong></p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">Os efeitos da toxina botul&iacute;nica s&atilde;o geralmente potencializados quando usada concomitantemente com antibi&oacute;ticos aminoglicos&iacute;deos (ex.: sulfato de gentamicina, sulfato de neomicina) ou outros medicamentos que interferem na transmiss&atilde;o neuromuscular (ex.: cloreto de tubocurarina).<br style="letter-spacing: 0.02em;" />Como consequ&ecirc;ncia, o relaxamento muscular pode ser potencializado e o risco de disfagia (dificuldade para engolir) pode aumentar.<br style="letter-spacing: 0.02em;" />Para mais informa&ccedil;&otilde;es, vide a Bula.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">&nbsp;</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;"><strong style="letter-spacing: 0.02em;">Posologia:</strong></p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">NABOTA&reg; &Eacute; UM MEDICAMENTO, E DEVE SER APLICADO SOMENTE POR PROFISSIONAL DE SA&Uacute;DE DEVIDAMENTE HABILITADO.<br style="letter-spacing: 0.02em;" />NABOTA&reg; deve ser injetado via intramuscular.<br style="letter-spacing: 0.02em;" />NABOTA&reg; n&atilde;o deve ser injetado no sangue.<br style="letter-spacing: 0.02em;" />Antes da inje&ccedil;&atilde;o do produto, reconstituir o p&oacute; liofilizado com uma solu&ccedil;&atilde;o salina est&eacute;ril, livre de conservantes.<br style="letter-spacing: 0.02em;" />O diluente recomendado &eacute; cloreto de s&oacute;dio 0,9% para inje&ccedil;&atilde;o.<br style="letter-spacing: 0.02em;" />Aspirar a quantidade necess&aacute;ria de diluente com a seringa de tamanho apropriado e injet&aacute;-la no frasco.<br style="letter-spacing: 0.02em;" />Como este produto pode se desnaturar por agita&ccedil;&atilde;o violenta, a inje&ccedil;&atilde;o do diluente deve ser feita com delicadeza.<br style="letter-spacing: 0.02em;" />Rejeitar o frasco se o v&aacute;cuo n&atilde;o causar a aspira&ccedil;&atilde;o do diluente para seu interior.<br style="letter-spacing: 0.02em;" />Registrar a data e a hora da reconstitui&ccedil;&atilde;o no espa&ccedil;o reservado no r&oacute;tulo do produto.<br style="letter-spacing: 0.02em;" />Para mais informa&ccedil;&otilde;es, vide a Bula.<br style="letter-spacing: 0.02em;" />Validade: 3 anos ap&oacute;s a data de fabrica&ccedil;&atilde;o.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">Registro MS n&ordm; 1.6425.0006.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">&nbsp;</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;"><strong style="letter-spacing: 0.02em;">Aplica&ccedil;&atilde;o:</strong></p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">P&oacute; liofilizado para solu&ccedil;&atilde;o injet&aacute;vel. Frasco-ampola contendo 100 unidades de toxina botul&iacute;nica A. Uso Adulto via intramuscular.</p><p style="letter-spacing: 0.02em; margin-top: 0px; margin-bottom: 1rem;">Indicado para melhora tempor&aacute;ria da apar&ecirc;ncia das rugas glabelares moderadas a severas associadas &agrave; atividade dos m&uacute;sculos corrugador e/ou pr&oacute;cero em adultos e tratamento da espasticidade focal dos membros superiores associada a acidente vascular cerebral em adultos.</p></div></div></div></div></div></div></div></div></div>